Opioids are destroying what was left of the fabric of America. Like Crack, before it. Cocaine before that. Heroin. The list goes on. People are desperately seeking an escape from the drudgery and insanity of this world, and it's current self-serving and misguided "leaders". We are having a crisis in all kinds of drug dependencies. Anti-depressants. Painkillers. We feel powerless with the sick people in power holding all the cards.
The problem is not the addicts behaving badly. The problem is what is driving them to addiction in the first place. What is causing their pain. These are truly the lost souls in the world, in this Karnival of today.
That's what this song is about.
Watch a TV commercial for any modern drug. Listen carefully to all the horrible possible side effects. Often the side effects (death?) are worst than the original problem. That's all the lyrics you need.